Wisdom has been defined as “the perception of the best end and the best means.” I would also define it as the ability to apply knowledge profitably and sensibly. 1 Corinthians 1:22-24 says, “For the Jews require a sign and the Greeks seek after wisdom: But we preach Christ crucified, unto the Jews a stumbling block, and unto the Greeks foolishness; But unto them which are called, both Jew and Greeks, Christ the power of God, and the wisdom of God.” This stands out to me because what the world seeks, they find the least of. Yet, what believers find, whether they knew it or not, they needed most. Even today, people still seek wisdom and the power of signs. God gives by revelation and by inspiration. Our knowledge of Him does not come from Scientifically searching for Him, but rather from God’s divine self-disclosure to us.
This passage is ironic, in that we see those looking for a sign, and they trip over the sign. Meanwhile, we see those looking for wisdom, and they are foolishly discounting the wisdom of the Almighty. That which is supernatural is beyond the natural; outside the natural. It really would be foolish to discount everything outside the natural world simply because you can't see it, much like discounting the existence of planets that contain water beyond our solar system. We can't see them. But, the fact that we stand below this knowledge does not make us ignorant. Only discounting that as impossible would make us truly ignorant. Knowing the limitations of your own mind is true wisdom.